产品货号：
Z11561
中文名称：
APOB抗体
英文名称：
Anti-APOB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-APOB Antibody |
| 指标别名 | Apo B 100;Apo B 48;APOB;ApoB100;Apolipoprotein B;Apolipoprotein B 100;FLDB |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | APOB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Apolipoprotein B recombinant protein (Position:Q246-N450).Human Apolipoprotein B shares 82.4% and 80.5% amino acid (aa) sequence identity with mouse and rat Apolipoprotein B,respectively. |
| 实际分子量 | 515KD/250KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene.This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins.It occurs in plasma as two main isoforms,apoB-48 and apoB-100:the former is synthesized exclusively in the gut and the latter in the liver.The intestinal and the hepatic forms of apoB are encoded by a single gene from a single,very long mRNA.The two isoforms share a common N-terminal sequence.The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA),resulting in the creation of a stop codon,and early translation termination.Mutations in this gene or its regulatory region cause hypobetalipoproteinemia,normotriglyceridemic hypobetalipoproteinemia,and hypercholesterolemia due to ligand-defective apoB,diseases affecting plasma cholesterol and apoB levels. |
| Uniprot ID | P04114 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | apolipoprotein B |
| 蛋白名全称 | Apolipoprotein B-100 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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